![]() When compared with the standard dual technique, it did not reach our predefined non-inferiority margin. Sentinel node biopsy (SNB) is the gold standard technique for lymph node staging in patients with primary cutaneous melanoma. The magnetic technique is feasible for SLNB in melanoma with a high SLN identification rate, but is associated with skin staining. Sentinel node biopsy is a procedure to see if cancer has spread. The lymph node retrieval rate was 1.99 nodes per patient overall, 1.78 with the standard technique and 1.87 with the magnetic technique. With radioisotope alone, the SLN identification rate was 95.3 % (123/129), as with the magnetic technique (0 % difference 95 % upper CL 4.5 7.8 % discordance). The sentinel node identification rate was 97.7 % (126/129) with the standard technique and 95.3 % (123/129) with the magnetic technique. The SLN identification rate per patient, with the two techniques, was compared.Ī total of 133 patients were recruited, 129 of which were available for final analysis. ![]() SLNB was undertaken after intradermal administration of both the standard (blue dye and radioisotope) and magnetic tracers. The MELAMAG Trial compared the magnetic technique with the standard technique for SLNB in melanoma.Ĭlinically node-negative patients with primary cutaneous melanoma were recruited from four centers. The magnetic technique is non-radioactive and provides a brown color change in the sentinel lymph node (SLN) through an intradermal injection of a magnetic tracer, and utilizes a handheld magnetometer. Sentinel lymph node biopsy (SLNB) in melanoma is currently performed using the standard dual technique (radioisotope and blue dye). SLN biopsy is based on an ordered dissemination of tumor cells from peritumoral lymphatics to the SLN, and then to more distant lymph nodes.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |